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Organic conversion

Phenol to anisole

1 step: Williamson synthesis

Class 12, Chapter 7 Alcohols, Phenols and Ethers

  1. HO
    PhenolC₆H₅OHPhenol
  2. Step 1

    (i) NaOH (ii) CH₃I

    Williamson synthesis
    i

    Williamson synthesis: sodium phenoxide plus a primary methyl halide.

    O
    AnisoleC₆H₅OCH₃Ether

Exam answer

  1. Step 1: Phenol to anisole: (i) NaOH (ii) CH₃I.
Why these reagents

Reagent and reason, step by step

  • Step 1: Phenol to anisole: (i) NaOH (ii) CH₃I Williamson synthesis: sodium phenoxide plus a primary methyl halide.
Questions

Phenol to anisole: quick answers

How many steps does it take to convert phenol to anisole?

1 step: Phenol, then anisole.

Which named reaction is used to convert phenol to anisole?

Williamson synthesis. An alkyl halide reacts with a sodium alkoxide (or phenoxide) to give an ether.

What is the reagent for step 1 of phenol to anisole?

Phenol to anisole: (i) NaOH (ii) CH₃I. Williamson synthesis: sodium phenoxide plus a primary methyl halide.

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